The Power of Placebos by Professor Jeremy Howick (1995 Social Studies) is an exploration of the science of placebos and nocebos, presenting a transformative perspective on healthcare. Drawing on over two decades of research and data from 300,000 patients, Howick dismantles misconceptions surrounding placebos, revealing their effectiveness in reducing pain, alleviating symptoms, and even mitigating doctor burnout.
The book delves into the physiological mechanisms behind placebo effects, demonstrating how the brain can trigger the body's internal pharmacy to produce endorphins, dopamine, serotonin, and endocannabinoids. Howick emphasises that placebos go beyond mere positive thinking, serving as powerful tools in medical treatment.
While highlighting the positive impact of placebos, Howick also explores the dark side of healthcare—the nocebo effect. Negative expectations about treatment can lead to severe side effects, amplifying pain, nausea, and anxiety, and in extreme cases, resulting in Voodoo-style death.
The book provides an interdisciplinary perspective, integrating history, philosophy, ethics, and science, challenging traditional practices and advocating for the ethical use of placebos in clinical trials and their regular incorporation into medical practice.